2017 ACEAT

2017 ACEAT
The Annual Conference on Engineering and Applied Science
Nov 6-9 , 2017, Fukuoka, Japan


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Keynote Speech
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CHENG, KUAN-CHEN Ph.D.
Associate Professor
Institute of Biotechnology,
National Taiwan University,
Taiwan
Topic: Production of Bacterial Cellulose and Its Application in Wound Healing
Summary of Keynote Speech
Bacterial cellulose (BC), produced by microorganisms such as Komagataeibacter xylinus, is used in wound healing applications due to its material properties, including the ability to maintain high-water content and good biocompatibility. Moreover, BC also presents regular network structure (typical crystalline form of cellulose Iα), which provides flexible material property and high strength. Numerous BC dressing studies are being investigated to improve wound healing characteristics through usage of different cultivation systems and surface modification of BC. Development of an ideal wound dressing to efficiently improve wound healing process is an important issue in wound care. The present study aims to cross-link dextran with bacterial cellulose (BC) to form a dextran/BC hydrogel, and to evaluate the performance of dextran-modified BC hydrogel in a mouse model. This is the first report to apply dextran/BC hydrogel as wound dressing. Our results indicated that the modified dressing - dextran/BC hydrogel - appears to contain a high-water content, rigid but flexible material properties, fine cell proliferation with non-cytotoxicity at the cell-based level, and excellent wound healing ability in vivo. The added dextran plays a key role in that it promotes fibroblast cell growth in the proliferation stage and also help skin maturation in the remodeling stage, causing the acceleration of the wound healing process. It is important to note that this is superior to the commercial wound dressings. Human studies are needed to further investigate the applications as a therapy for different types of wounds.

Venue
Hotel Okura Fukuoka
ADD 〒812-0027 Hakata Riverain 3-2 Shimokawabata-machi, Hakata-ku, Fukuoka
TEL 81-92-262-1111
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Important Dates
Submission Deadline
July 15 / 2024
Notification of Acceptance
August 01 / 2024
Early Bird Registration Deadline
August 20 / 2024
Registration Deadline
September 05 / 2024
Conference Dates
November 14-16, 2024
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